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The use of AACSB accreditation as an
2020-08-22
The use of AACSB accreditation as an indicator of expected performance on the CPA exam has been examined by prior studies (e.g. Barilla et al., 2008, Boone et al., 2006, Grant et al., 2002, Howell and Heshizer, 2006, Lindsay and Campbell, 2003, Marts et al., 1998). While these studies are based on d
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Several TERRA binding proteins have also
2020-08-22
Several TERRA-binding proteins have also been discovered, especially telomeric duplex DNA binding proteins TRF1 and TRF2, pointing to a significant role of TERRA in more general chromosome biology [14], [20], [21]. TRF2 is a key component of Shelterin that protect chromosome termini [22]. Telomeres
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C527 br Introduction Rhabdomyosarcoma RMS is a myogenic tumo
2020-08-22
Introduction Rhabdomyosarcoma (RMS) is a myogenic tumor that accounts for approximately 50% of all pediatric soft tissue sarcomas. Diagnostic criteria for RMS C527 on the validation of proteins of the skeletal muscle lineage, such as Desmin, MyoD or Myogenin [1]. RMS cells are persistently kept
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It has been reported that Eph Ephrin are
2020-08-22
It has been reported that Eph/Ephrin are involved in the regulation of the tumor angiogenesis [10], [11], [12]. The distinct and specific involvement of CBR-5884 and veins in tumor angiogenesis is unclear. EphrinB2 is expressed in arteries and its receptor EphB4 is expressed in veins; these molecul
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Prostaglandins PGs in particular PGE and PGF play
2020-08-22
Prostaglandins (PGs), in particular PGE2 and PGF2α, play pivotal roles in human parturition by stimulating cervical ripening, myometrial contraction and fetal membrane rupture (Challis et al., 1997). In human pregnancy, the amnion is the principle source of PGE2 (Duchesne et al., 1978). In the amnio
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The following are the supplementary data related to this art
2020-08-22
The following are the supplementary data related to this article. Acknowledgments Introduction Cyclooxygenases metabolize arachidonic Calcium Ionophore I to five primary prostanoids, PGE2, PGF2, PGI2, TXA2 (TX), and PGD2. These lipid mediators interact with specific members of a family of dis
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96 4 ICT is a product of icariin via the metabolism
2020-08-21
ICT is a product of icariin via the metabolism of intestinal bacteria with estrogen-like activities [33]. ICT as a bone-protecting agent can enhance osteoblast differentiation while suppressing osteoclastic differentiation in vitro [19], and stimulate osteogenic differentiation and inhibit adipogene
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Hepatic steatosis is strongly associated with insulin resist
2020-08-21
Hepatic steatosis is strongly associated with insulin resistance. Numerous studies in humans and animals have shown that insulin-resistant states are often accompanied by hepatic steatosis (Angulo and Lindor, 2001, Marchesini et al., 1999, Marchesini et al., 2005, Petersen and Shulman, 2006, Seppala
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br Materials and methods br Results br Discussion In
2020-08-21
Materials and methods Results Discussion In this study, we developed a new CysLT1 and CysLT2 receptors-mediated Caspase-4 Colorimetric Assay Kit guinea pig model for screening both CysLT2 receptor and CysLT1/2 receptor antagonists. Unlike human CysLT2 receptors, which are equally stimulate
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Prostaglandins PGs are lipid mediators that
2020-08-21
Prostaglandins (PGs) are lipid mediators that exhibit a variety of physiological properties by interacting specific G protein-coupled receptors (GPCRs) [10]. PGD2 is synthesized from PGH2 through two distinct PGD synthases; lipocalin-type PGD synthase (L-PGDS) and hematopoietic PGD synthase (H-PGDS)
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Unlike CRM exportins Cse and Xpot
2020-08-21
Unlike CRM1, exportins Cse1 and Xpot lack a C-extension and instead rely primarily on changes in HEAT-repeat conformation and direct Ran-cargo contacts to ensure low cargo-binding affinity in the cytosol and cooperative assembly of the exportin/Ran/cargo complex in the nucleus (Cook et al., 2005, Co
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Alternatively procedural factors may have contributed
2020-08-21
Alternatively, procedural factors may have contributed to the conflicting results. For instance, in order to have a more circumscribed area of drug diffusion, a volume of 0.05μl was injected in experiment 1b, which is four times lower than the one used in the mentioned plus-maze investigation. Besid
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br Collagens as new drivers of
2020-08-21
Collagens as new drivers of zebrafish tissue regeneration Contrary to mammals, zebrafish possess very high regeneration capacities and thereby represent a versatile model to study tissue and organ regeneration. Adult fish can fully reconstruct their brain, spinal cord, retina, kidney, liver, panc
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We did not observe inhibition of vCPH by any
2020-08-21
We did not observe inhibition of vCPH by any of the TCA cycle intermediates (apart from the metal chelators citrate and isocitrate), nor by the factor inhibiting HIF (FIH; a 2OG-dependent asparaginyl hydroxylase) inhibitor N-oxalyl d-phenylalanine (NOF) or the γ-butyrobetaine dioxygenase inhibitor m
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br Results and discussion br Conclusions We
2020-08-21
Results and discussion Conclusions We have developed a method to produce wildtype and mutant Ric-8A proteins from E. coli that can be phosphorylated at the regulatory protein kinase CK2 phosphosites to near homogeneity. The phosphorylation status and activity of the purified Ric-8A proteins wa
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