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br Community based bundled health interventions
2019-04-20
Community-based bundled health interventions are complex and challenging to implement, monitor, and assess in informal settlements (slums). Such settlements in urban areas are generally characterised by congestion, squalid conditions, deprivation, violence, crime, and poor sanitation. In Asia and
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br Methods br Results br Discussion It
2019-04-20
Methods Results Discussion It is almost certain that PHMG-p caused interstitial fibrosis in humans due to inhalation exposure. Many epidemiological and toxicological studies have demonstrated that PHMG-p causes inflammatory and fibrotic responses in cells, animals, and humans [1,2,4,9,10].
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br In the past decade Brazil
2019-04-19
In the past decade, Brazil has achieved considerable progress in malaria control, with 140 000 cases reported in 2015, the lowest numbers since 1980. Part of this success has been attributed to the establishment of a large network of around 3000 diagnostic and treatment units for malaria. A remark
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Introduction This document does not address
2019-04-19
Introduction This document does not address the indications of genetic testing in patients affected by inherited arrhythmias and their family members. Diagnostic, prognostic, and therapeutic implications of the results of genetic testing also are not included in this document because this topic has
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br Does ambulatory monitoring prevent HF decompensation
2019-04-19
Does ambulatory monitoring prevent HF decompensation? While vigilant monitoring of symptoms and signs (and BNP levels) is useful, it does not guarantee the accurate prediction of ADHF. On the other hand, frequent monitoring of some of these signs and symptoms and the use of external physiological
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Examples of numerically generated vortices and their
2019-04-19
Examples of numerically generated vortices and their organizing centers in 3-D excitable media are illustrated in Fig. 1. Panels a to d show 4 different configurations of 3-D scroll waves that were computed using the FitzHugh–Nagumo model [39,40]. Panel a shows an example of the simplest configurati
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In bone microenvironment OPG RANK RANKL molecular triad
2019-04-19
In bone microenvironment, OPG/RANK/RANKL molecular triad is not solely expressed by bone cells. Whether OPG is considered as a ubiquitary receptor [20], membrane RANK is expressed by various tumour fasudil that originate from primary bone tumours or bone metastases, from mesenchymal and epithelial
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In this study we applied a more
2019-04-19
In this study, we applied a more general approach along these lines, which has previously been used only in few reports in the literature [8]. Based on a prospective BC database including all newly diagnosed BC cases at a large Swiss breast center over a 20-year period, we aimed to give a comprehens
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br Results br Discussion The
2019-04-19
Results Discussion The results of this retrospective study demonstrate the feasibility and safety of combined left atrial catheter ablation and Watchman® implant procedures with satisfactory LAA occlusion maintained at follow-up. The rates of successful device implantation and complete LAA occ
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En cuanto a Semana los
2019-04-19
En cuanto mst2 “Semana…”, los cambios de las lecciones son poco sig-nificativos: «noble» M por «limpia» M1 (v.11); el uso de paréntesis o letras mayúsculas para los títulos de cada fragmento del poema. Esta semana poetizada no sigue un itinerario corriente, pues carece de miércoles en la edición ori
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br Discussion Chronic myelogenous leukemia CML is
2019-04-18
Discussion Chronic myelogenous leukemia (CML) is a clonal disorder involving the pluripotent stem cell and is consistently associated with the BCR-ABL1 fusion gene located on the Philadelphia chromosome [1]. The disease typically evolves in 3 distinct clinical stages: chronic and accelerated phas
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bax pathway A critical link exists between awareness of
2019-04-18
A critical link exists between awareness of risk, the presence of disease, and steps taken by the patient and clinician to change the natural history of disease. Chronic illnesses such as diabetes mellitus, dyslipidaemia, anaemia and a multitude of endocrinological and rheumatological diseases are r
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One day after implantation diaphragmatic stimulation was obs
2019-04-18
One day after implantation, diaphragmatic stimulation was observed when the patient was in the seated position, and it could not be resolved by reprogramming the device. We decided to replace the LV lead; however, there were no other vein branches suitable for CRT in the lateral region of the LV (F
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The patient had an implanted Medtronic SECURA
2019-04-18
The patient had an implanted Medtronic SECURA DR device (atrial lead: Medtronic 6940/52cm, ventricular lead: Medtronic 6945/65cm). The MRI machine used was a GE Signa HDx 1.5-Tesla system. Before performing MRI, we referred to the European position statement on MRI in patients with CIEDs [3]. Becaus
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Bisphosphonates significantly reduce or prevent SREs The
2019-04-18
Bisphosphonates significantly reduce or prevent SREs. The use of Zol for patients with bone metastases is currently the gold standard treatment [4]. However, it is still unclear whether Zol contributes to a survival benefit [9]. Niikura et al. recently reported that Zol did not prolong progression-f
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